
产品货号:
Z16400
中文名称:
FMO3抗体
英文名称:
Anti-FMO3 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-FMO3 Antibody |
指标别名 | Dimethylaniline oxidase 3;FMO 3;FMO form 2;FMO II;FMO3;FMOII;TMAU |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB |
基因名称 | FMO3 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human FMO3 (404-433aa DMMNDINEKMEKKRKWFGKSETIQTDYIVY),different from the related mouse sequence by eight amino acids,and from the related rat sequence by six amino acids. |
实际分子量 | 60KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | FMO3 (Flavin-containing Monooxygenase 3) is an enzyme that in humans is encoded by the FMO3 gene.The mammalian flavin-containing monooxygenases (FMO) represent a multigene family whose gene products are localized in the endoplasmic reticulum of many tissues.The FMO3 gene contains 1 noncoding and 8 coding exons.And the FMO3 gene is mapped on 1q24.3.Using quantitative RNase protection assays,FMO3 is present in low abundance in fetal liver and lung and in adult kidney and lung,and in much greater abundance in adult liver.By Western blot analysis of human liver microsomal samples ranging from 8 weeks gestation to 18 years of age,FMO1 is the major fetal isoform and FMO3 is the major adult isoform.FMO3 was expressed at intermediate levels until 11 years of age when a gender-independent increase in FMO3 expression was observed during puberty.Sufferers of trimethylaminuria may display a reduced ability to metabolize substrates for FMO3 such as nicotine.FMO3 metabolizes a number of drugs,including amphetamine,clozapine,deprenyl,metamphetamine,tamoxifen,ethionamide,thiacetazone,and sulindac sulfide. |
Uniprot ID | P31513 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | flavin containing monooxygenase 3 |
蛋白名全称 | Dimethylaniline monooxygenase [N-oxide-forming] 3 |
推荐稀释比 | Western blot(WB) 1:500~2000 |
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